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     海法大学生物博士后开始招生

    [字号: ]
    2015-03-22

    Institute of Evolution ????????? ?????

    Bioinformatics Post-Doc Positions

    University of Haifa, Haifa, Israel

    You can be part of a fascinating project of a breakthrough in cancer treatment

    Looking for independent, motivated candidates with a proven background in bioinformatics and biology and good analytical skills, to reveal the mechanisms of cancer-resistance and anti-cancer activity of the

    Israeli Subterranean, Blind Mole-Rat, Spalax

    This unique mammal is hypoxia- tolerant (down to 3% O2), oxidative-stress adapted, long lived (>20 years; ~4-5 times longer than its relative, the rat) and cancer-free. No spontaneous tumors have ever been observed in thousands of individuals along >40 years of studies. Moreover, Spalax is highly resistant to chemical carcinogens-induced tumor development, which led to the expected cancer in 100% of mice and rats. Most fascinating, Spalax fibroblast cells, but not of other species, secrete substance/s, yet to be identified, that lead to the death of cancer cells (but not of normal cells) from different species, including human cancer cells originated from a wide range of tissues (Manov et al., BMC Biol, 2013).

    We recently sequenced its genome and discovered its unique organization (Fang et al., Nat. Comm, 2014). Further, differential gene expression from RNAseq data has revealed enrichment of genes that overlap cancer resistance, apoptosis, angiogenesis, and hypoxia-tolerance. (Malik et al., BMC Genomics, 2013)

    We want to understand how these changes are translated into protection from cancer, so we can develop novel treatment strategies.

    Applicants should be able to process large scale genomic data, such as raw RNA-seq, miR seq and Genomic sequencing, analyze the data, and biologically interpret it in high level. Accordingly, background in statistics, programming and scripting is required. (e.g., experience and knowledge in tools like Linux clusters, R, mysql, Matlab, perl, python, etc.). Background in cancer research and familiarity with TCGA [TheCancerGenomeAtlas] is an advantage.

    We can offer generous fellowships to candidates that will commit themselves for at least 2 years with a willingness to extend the period of their studies according to the needs of their project.

    Qualified applicants that can fulfill our expectations-Please submit an extended CV andbibliography, summary of past accomplishments, list of (importantly 1st authorship and peer-reviewed, respected impact factor journals) publications, and contact information of 3 referees to Dr. Aaron Avivi ( [email protected]l) AND Dr. Imad Shams ( [email protected]m)

    ( //evolution.haifa.ac.il/index.php/29-people/personal-websites/77-personal-site-avivi)

    Mount Carmel, Haifa 3498838, Israel, Phone: 972-48240446 :'?? 3498838 ???? ,????? ??

    Website: ///evolution.haifa.ac.il :??????? ??? Fax: 972-482465554:??? E-mail: [email protected] :?"???

     
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  • 河北省大气环境问题曝光台 2019-08-05
  • 房价炒成这个样子,还不准说,像话么? 2019-08-04
  • 山东省将举办“第十二届全国美展山东作品展” 2019-08-04
  • 全世界最美的办公室都在这里了 快来一饱眼福 ——凤凰网房产 2019-07-25
  • 老痴呆:家庭也有计划经济,知道吗? 2019-07-10
  • 呼和浩特市:绿化持续完善 建设绿色青城 2019-07-10
  • 中国现在大学毕业水平人口有近一亿,20年后是3.5亿,比美国总人口还多,硕士生将达到2千5百万,博士2百万。这就是20年后中国的实力,不管美国怎样折腾都是没用的 2019-07-05
  • 以“上海精神”开辟合作发展新境界 2019-07-03
  • 亓庆良:山村里也有了健康中国“大梦想” 2019-07-03
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  • 爬窗户干瞪眼  云南文山一小区惊现倭蜂猴 2019-06-19
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